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Researchers have since used chemical analyses to study the ancient use of tobacco and other intoxicants in regions throughout the Americas

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The data from NCBI-Gene and UniProt were used to show the expression and health risks of tobacco smoking associated with nine genes related to the initiation of smoking and nicotine dependence, and four genes linked to lung cancer (Table 1)

Average HR for smokers was 82.5 14.56/min, and maximum and minimum HR was 123/min and 55/min, respectively

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