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Familial Adenomatous Polyposis (FAP), linked to APC gene mutations, leads to hundreds to thousands of colon polyps, and nearly 100% of untreated individuals with FAP will develop colorectal cancer by age 40 (World Health Organization)

Sattar N, Lee MMY, Kristensen SL, Branch KRH, Del Prato S, Khurmi NS, et al

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