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For instance, impulsive, uncontrolled behavior is seen in adults with orbitofrontal lesions [97] There is a relationship between dysfunction of the limbic system and irregularities in orbitofrontal cortex development

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"Sometimes it involves contralateral or lymph nodes that are on the opposite side of the neck where the primary tumor began." "Patients who have disease that has spread outside of the head and neck region, meaning below the clavicles, into the lungs or into the liver, we call that distant metastatic disease and by definition those patients are considered incurable," she continued