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The criteria apply to marijuana as well as other drugs, like opioids and alcohol

To relax the log(linear) assumption usually applied to continuous doseresponse risk and make the estimates robust to the placement of spline knots, we used an ensemble spline approach to fit the functional form of the doseresponse relationship

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Moodie C, Thrasher JF, Cho YJ, Barnoya J, and Chaloupka FJ

The goal of this paper is to provide evidence for the FDA as it defends its intention to remove menthol cigarettes and cigars from the U.S