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Despite a global decline in smoking, the number of young people smoking menthol cigarettes has not decreased

A population of cells in individuals with a history of smoking had mutational burdens that were equivalent to those expected for people who had never smoked: these cells had less damage from tobacco-specific mutational processes, were fourfold more frequent in ex-smokers than current smokers and had considerably longer telomeres than their more-mutated counterparts

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However, among those who ever smoked cigarettes, a significantly higher percentage of girls reported an earlier age of initiation compared to boys