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Moreover, nicotine exposure from non-cigarette products was not examined here, and the directionality between smoking and depression cannot be fully disentangled given evidence that depression may influence smoking behavior [16]

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Because nicotine lives at the core of both the problem and the solution to the question of addiction, addressing the addictive levels of nicotine in combustible cigarettes must be part of the FDAs strategy for addressing the devastating, addiction crisis that is threatening American families, said Scott Gottlieb, the FDA commissioner

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This narrowing can cause the angina, stroke or heart attack, he added