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It requires the smoker to be actively trying to reduce their smoking by replacing it with e-cigarette use. The researchers conducted a randomized controlled trial of 520 participants who smoked more than nine cigarettes a day, were not currently using an e-cigarette device, and were interested in reducing smoking but not quitting

And though only mumbles can be heard on the other end, we know its Eli by the look on Willies face

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12 (2), e0172196

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These include six cost-effective interventions to reduce tobacco exposure and two on the management of COPD