cigarette smoke mitochondrial depolarization lung epithelial cells causes a bioenergetic crisis in RPE involving the downregulation of HIF-1α under normoxia Nicotine affects mitochondrial structure and

Nicotine affects mitochondrial structure and function in human airway smooth muscle cells American Journal of Physiology Lung Cellular and Molecular Physiology American Physiological Society Mitochondrial dysfunction in fibrotic diseases Cell Death Discovery Effect of cigarette smoke extract on mitochondrial heme metabolism: An in vitro model of oral cancer progression ScienceDirect A chronic whole cigarette smoke extract model reveals redoxmitochondrial adaptation in human lung epithelial and organoid models Experimental & Molecular Medicine Cigarette smoke can reprogram cells in your airways, causing COPD to hang on after smoking ends Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium Nature Communications

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