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In the context of vaping, pulmonary functional MRI sensitively revealed ventilation and perfusion abnormalities in e-cigarette users following acute exposure to e-cigarettes (107, 108), and in a patient recovering from EVALI (61)

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It has been reported that up to 40% of particles emitted by an electronic cigarette can deposit in the deepest areas of youth lungs, and that chemicals contained in these particles may irritate airways or worsen pre-existing respiratory conditions such as asthma and bronchitis.[10] The US National Academy of Sciences, Engineering and Medicine also concluded in their report that vapour from e-cigarettes can induce acute endothelial cell dysfunction, and can promote formation of reactive oxygen species and induce oxidative stress which may lead to tissue injury and disease[11]

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1992 Tobacco Control 1 : Suppl S52S56 Pierce JP, Gilpin EA, Emery SL, White MM, Rosbrook B, Barry CC