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N-acetylcysteine and Glutathione N-acetylcysteine, an antioxidant, activates glutathione peroxidase, resulting in an increase in the whole blood concentration of glutathione [17]

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Preclinical studies in Alzheimers disease models have demonstrated that pharmacological inhibition of ferroptosis with small-molecule inhibitors such as ferrostatin-1 or liproxstatin-1 alleviates lipid peroxidation, neuronal death, and cognitive decline (Bao et al., 2021