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Declaration of interest This work was supported by the National Natural Science Foundation of China (No

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68 Novel hypoglycemic agents, on the other hand, include dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, and modified insulin analogs, which not only provide effective glycemic control but also confer additional benefits such as weight reduction and cardiorenal protection

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