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Many believed that it could dissolve gallstones, cure asthma, relieve headaches and disinfect open wounds, Andrew Lawler writes in his book A Perfect Frenzy, Tobacco became a cash crop that fueled the colonial economy and played a key role in financing the American Revolution

Figure 2 illustrates this for both survey types

As well, total leukocytes were significantly higher, driven by increases in granulocytes and monocytes

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