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Cigarette smoke passes through the lungs to the heart, then spreads throughout the body via the blood

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Since electronic cigarettes, commonly known as e-cigarettes, first hit the market in 2007, theyve become a popular option for people who want to stop smoking and people who have never smoked traditional cigarettes

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[16] E-liquid exposure whether intentional or unintentional from ingestion, eye contact, or skin contact can cause adverse effects such as seizures and anoxic brain trauma

This review focuses, as shown in the graphical abstract, primarily on the gastrointestinal system's diseases associated with nicotine addiction as well as the mechanisms of action, pharmacokinetics, and metabolism of the drug