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The two studies that evaluated the effect of smoking on mirtazapines pharmacokinetics show significantly lower mirtazapine and their main active metabolites (S-mirtazapine and R-N-desmethylmirtazapine) serum levels in smokers than in nonsmokers

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95% CI, 0.250.89) [24]

One of the most dangerous among them is formaldehyde a known carcinogen customarily used to preserve dead bodies

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