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Indistinguishable from adult animals, VTA GABA neurons from P21 to P28 rats receiving nicotine showed a significantly more depolarized E GABA value compared with saline-treated controls: 63.8 4.3 mV after nicotine, 87.6 2.4 mV after saline, n = 7, n = 8 cells/group, n = 4, n = 5 rats/group, t = 4.956, p = 0.000 (Table 1, line a)

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The author (Koufman) examined the reflux testing (pH-monitoring) data of 750 known (smoking and non-smoking) reflux patients and showed that reflux was twice as severe in smokers

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