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According to a review of public health studies of farmworkers, pesticide exposure is associated with acute health problems including nausea, dizziness, vomiting, headaches, abdominal pain, and skin and eye problems.[108] Exposure to large doses of pesticides can have severe health effects including spontaneous abortion and birth deformities, loss of consciousness, coma, and death.[109] Long-term and chronic health effects of pesticide exposure include respiratory problems, cancer, depression, neurologic deficits, and reproductive health problems.[110] Children are uniquely vulnerable to the adverse effects of toxic exposures as their brains and bodies are still developing, and they consume more water and food, and breathe more air, pound for pound, than adults.[111] The US Environmental Protection Agency (EPA) estimates that 10,000 to 20,000 physician-diagnosed pesticide poisonings occur each year among US agricultural workers.[112] One public health study found that 64 percent of acute occupational pesticide-related illnesses reported by children occurred among children working in agriculture, and this number represents only a small fraction of actual pesticide poisonings as many cases are never reported.[113] The EPA has established federal regulations called the Worker Protection Standard, which require labeling of pesticides, notification of workers about pesticide application, safe application of pesticides, access to emergency medical assistance, and the provision of decontamination supplies, pesticide safety training and safety posters, and personal protective equipment.[114] The EPAs Worker Protection Standard does not specify a minimum age for children to mix and apply pesticides, but regulations set by the US Department of Labor (DOL) under the Fair Labor Standards Act prohibit children under 16 from handling pesticides belonging to the two most toxic categories, as determined by the EPA.[115] In addition, the EPA sets restricted entry intervals (REIs) specifying the amount of time after pesticide application that workers should not enter the fields without wearing protective equipment.[116] REIs vary depending on the toxicity of the pesticide, the type of crop, and the method of application, and may last from a few hours to a few days.[117] However, public health studies have shown that, even if workers are kept out of the area for the legally required time period, pesticides are still present in the fields at lower levels.[118] Furthermore, federal regulations make no special considerations for children, and the EPA determines restricted entry intervals using a 154-pound (70-kilogram) adult body as a model.[119] In February 2014, the EPA proposed changes to the agricultural Worker Protection Standard
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