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Apart from their effects on monoamine neurotransmitters and the downregulation of receptors that can treat comorbid mental disorders, antidepressants have a neuromodulator role that mediates visceral sensitivity, gut motility and secretion and has immunoregulatory and anti-inflammatory effects, while shifting the composition of gut microbiota

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The marketing of menthol cigarettes has been banned in the European Union since May 20, 2020

Until recently, nicotine was known only as an addictive substance with no cancer-causing effect, and the production of electronic cigarettes was based on this information

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