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We further analysed the activities of mutants C110S/C130S TEV and C110G/C130G TEV

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Its been around for centuries, tracing back to Indigenous tribes in the Americas who used ground tobacco leaves for spiritual and ritual purposes

Since current samples have low prevalence of EC use among PWNS, some of the existing studies reviewed here may have insufficient statistical power, particularly when thoroughly adjusting for confounding factors, and may have therefore missed true significant associations