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COX-2 is a potent enzyme that can initiate inflammation and promote the synthesis of prostaglandins after being stimulated, and it plays a critical role in the onset and development of liver fibrosis []

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284,285,286 Moreover phase I clinical trial has shown that the combination of DSFCu and temozolomide has an acceptable safety profile and increases progression-free survival in patients with glioblastoma 287 (Table 1)

About the Author About the Author Jon Grant, MD, JD, MPH, is a Professor of Psychiatry at the University of Chicago