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23,24 Furthermore, the acidic nature of some e-cigarette liquids, with a pH often below 5.5, raises concerns about erosive potential

Airway epithelium contain motile cilia which are an integral part of the mucociliary escalator, removing fluids, mucins, and particulates from the airway [33, 34]

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Reviewing the evidence A joint position statement from Cancer Council Australia and the Heart Foundation makes detailed recommendations for regulation, and says the limited evidence available points to a risk that widespread electronic cigarette use could undo the decades of public policy work in Australia that has reduced the appeal of cigarette use in children and that the short and long term health effects of electronic cigarette use remain unknown

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A lot of research has also linked adolescent marijuana use with a range of negative consequences, including cognitive deficiencies and worse educational outcomes