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A lack of saliva allows plaque to grow more rapidly

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Given that most of the included studies were observational in nature, the influence of unmeasured confounders cannot be completely eliminated, and caution is warranted when interpreting these findings in terms of causality

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Acknowledgments The authors would like to thank Jamie Humphrey, Lan Margosis, Zahra Ehtesham, and Donna Vallone, who provided invaluable support