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V: The images for this cover story were shot by Hedi Slimane

In addition to containing varying levels of the addictive substance nicotine, they also contain other cancer-causing chemicals, such as formaldehyde, and as our study shows, flavoring chemicals that can cause lung damage, said study co-author David Christiani, Elkan Blout Professor of Environmental Genetics

S ince at least the colonial era, tobacco has been a popular commodity in the United States, with tobacco use increasing almost exponentially from the 1800s to the mid-1960s (DHHS 2000a)