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However, there is limited, but consistent evidence from case reports that very high doses of PG administered orally or intravenously to humans can produce toxic effects that appear to be related to osmolar changes in the blood and lactic acid formation secondary to the metabolism of PG

That being said, since knowledge of the possible harms of X is widespread, any individual who engages in X must be held responsible for any harms that X causes. This is not just an argument about smoking

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