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2 and described in detail in the Ca 2+ signaling, ROS signaling, Ceramide signaling, Eryptosis and caspases, Crosstalk between eryptosis and necroptosis in erythrocytes: Is caspase-8 involved?, Eryptosis-associated kinases, Extrinsic Fas-mediated eryptosis, Nitric oxide signaling, GTPase signaling, and Cellular energy metabolism and eryptosis sections Ca 2+ signaling Ca 2+ plays an important role in apoptosis signaling of nucleated cells [96]