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22 In addition, deubiquitinating enzymes (DUBs) regulate mitophagy by deubiquitinating Parkin or its targets on the mitochondrial, and Parkin can mediate nuclear translocation of transcript factor EB (TFEB), thereby upregulating the expression of genes associated with lysosome biogenesis (Fig

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The use of nicotine in adolescents may also affect learning, memory and cognitive abilities

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