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While there are factors known to hike the risk of the condition, smoking has often been highlighted as the worst culprits

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Srivastava S, Sajid M, Singh H, Bharadwaj M (2022) Delineating the bacteriome of packaged and loose smokeless tobacco products available in North India

Varenicline is termed a partial agonist, as it partially binds to these nicotinic receptors, helping to reduce nicotine withdrawal symptoms and cravings