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Studies have identified genetic variants associated with both nicotine dependence and alcohol dependence, suggesting a shared genetic susceptibility which increases the likelihood of drinking and smoking heavily

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Analysis of data from the 2014-2015 Tobacco Use Supplement to the Current Population Survey found that those who started smoking before the age of 18 were 2.15 times as likely to become nicotine dependent in their lives, compared to those who started smoking at age 21 or older

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