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4318-A MESENCHYMAL STEM CELLS SMALL EXTRACELLULAR VESICLES PROMOTE HEPATOCYTE REGENERATION VIA ATTENUATING MACROPHAGE EXTRACELLULAR TRAPS Zhihui Li 1 , Jing Zhang 2 , Shibo Meng 1 , Weizhen Weng 1 , Junyi Wang 1 and Bingliang Lin 1 , (1)The Third Affiliated Hospital, Sun Yat-Sen University, (2)Department of Infectious Diseases, Third Affiliated Hospital of Sun Yat-Sen University Background: Acute liver failure (ALF) is a a severe clinical syndrome characterized by dysregulated immune response and extensive hepatocytes death without effective therapies

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