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Notably, the primary addictive component of tobacco is nicotine, an alkali substance that swiftly enters the bloodstream and rapidly crosses the blood-brain barrier, leading to its profound addictive properties

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Government policies and market expansion support: Governments are promoting reduced-risk products and are actively supporting harm reduction

In practice, however, almost everyone depends on a supply through the diet

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"Assessing the effect of waterpipe smoking on cancer outcome a systematic review of current evidence"