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Although popular reports of its ability to raise testosterone levels have led to its common use to treat problems related to male sexual function, including erectile dysfunction and low sexual desire, clinical trials have yielded mixed findings

doi: 10.1016/j.biomaterials.2014.08.020

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in fact, it plays a critical role in both systemic and peripheral tissue inflammation and triggers high levels of pro-inflammatory cytokines tumor necrosis factor-alpha (TNF-) or interleukin-1/6 (Il-1/6) that have been indicted as the main cytokines secreted by macrophages and adipose tissue [18], creating a not-favorable microenvironment that impairs adipose tissue stem cells (ASC) multilineage differentiation potential [19], viability, and apoptosis, as well as autophagy and mitophagy [20] as well as oxidative stress that impairs ASC immunomodulatory potential [21]

This involves the alignment of collagen fibers and the strengthening of the extracellular matrix , which are essential for restoring the structural integrity and function of the injured area