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Indian J Med Paediatr Oncol 36(1):60-1, 2015

In cis signaling, IL-6 forms a complex with the membrane-bound IL-6 receptor (mIL-6R) and gp130 which then activates downstream the Janus kinases 1 (JAK1) and signal transducer and activator of transcription 3 (STAT3)

Data shown are from 3 independent experiments

Cells 12, (2023), Abstract Discovery of a novel dual functional phenylpyrazole-styryl hybrid that induces apoptotic and autophagic cell death in bladder cancer cells: S.W

It protects neurons from oxidative damage, supports mitochondrial function, and may reduce the risk of neurodegenerative diseases such as Alzheimers and Parkinsons