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Bilirubin - Direct, Serum Basic Checkup Boosts hair growth and follicleBilirubin Direct, Serum Test The Bilirubin Direct, Serum test measures the level of direct (conjugated) bilirubin in the blood. Bilirubin is a yellow pigment produced during the normal breakdown of red blood cells. Direct bilirubin is processed by the liver and excreted through bile. This test helps evaluate liver function and detect liver or bile duct disorders. Why is this test done? Doctors may recommend this test to: Assess liver health and