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Glucosylceramide synthase inhibitors have been shown to reduce the levels of glucosylceramide and glucosylsphingosine in the central nervous system, decelerate the accumulation of -syn, ubiquitin and tau proteins and improve cognitive and behavioral outcome in a GBA-associated PD mouse model (Sardi et al

Thats where glutathione steps in - it sits inside the mitochondria like a live-in cleaner, mopping up reactive oxygen before it can cause chaos

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As in most modern efforts to circumvent aging, Belmonte was tricking the bodyborrowing a powerful mechanism from embryos and, very gingerly, applying it to adults