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von Elm E, Altman DG, Egger M et al (2007) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies

In addition to energy production, mitochondria perform multiple other functions including Ca 2+ homeostasis [86, 87], generation of ROS [88], regulation of apoptosis [89], activation of endoplasmic reticulum-stress response [90], as well as other far-ranging sequelae of mitochondrial dysfunction [91]

Ebselen promotes formation of the SOD1 disulphide bond To determine whether ebselen exerts a protective role against SOD1 in the cytosol, its effect on intracellular SOD1 maturation was investigated in live human cells by in-cell NMR 32,33