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For example, the association between NOD2 and autophagy pathway genes is weaker in East Asian populations, whereas the association between IL23R/Th17 pathway genes is more pronounced in East Asian populations [178, 202]

Synaptic Plasticity Estrogens also have a neuroprotective role favoring synaptic formation, a process required for the survival of new neurons

8 Clinical trials have suggested that NR supports heart health, brain health, healthy body composition, and muscle health

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Targeting BCAT1 combined with alpha-ketoglutarate triggers metabolic synthetic lethality in glioblastoma

NETs also inhibit bile acid efflux pumps (BSEP) via the FXR signaling pathway, leading to the accumulation of toxic bile acids (e.g., deoxycholic acid [DCA]), which activate the TGR5 pathway in hepatic stellate cells, promoting fibrosis