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second, patients who were not eligible for LT

Strategies to boost the endogenous antioxidant defenses are highly desired

Allopurinol is generally well tolerated with rare but well described side effects that range from mild to potentially life threatening

Further studies are warranted to assess the efficacy of BTTs on PKU and A1AT deficiency in small animal models

have shown that QP could promote IL-4 secretion by helper T cells, decrease IL-1 and TNF- expression, reduce production of reactive oxygen species by macrophages, and prevent caseous necrosis (Butov et al., 2016)

Alveolar GSH is likely to be very important in HIV-infected individuals as well