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Oxygen in metabolic dysfunction and its therapeutic relevance

Further comprehensive investigations are required to validate these results, including mechanistic studies to elucidate the underlying pathways

Clinically, this can manifest as: Brain fog Fatigue Post-exertional crashes Mitochondrial Dysfunction in Long COVID If inflammation persists and coagulation pathways remain activated, mitochondria suffer

While the experimental models employed in PD have shown connections to human health, it remains a daunting task to translate mechanisms of action observed in in vitro and in vivo studies of natural compounds to clinical outcomes in human trials, where it is a critical step in drug development

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For remaining experiments adult animals at an age of 1012 weeks were used