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Recent nano-emulsion-based formulations have further improved skin penetration and delivery efficiency [123, 126], while curcumin emulgels have demonstrated symptomatic improvement in preclinical models [50, 124]

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Once you know the concentration in mg/mL, a dose in mg becomes a volume in mL by simple division, and that volume becomes insulin-syringe units by multiplying by 100 (because a U-100 syringe is marked so that 1 mL = 100 units)