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This release leads to a variety of effects: Dopamine Release: The release of dopamine in the brain's reward pathways creates feelings of pleasure and satisfaction, reinforcing the desire to consume nicotine repeatedly

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Psychopharmacology 107(1):110 Becker AM, Holze F, Grandinetti T et al (2022) Acute effects of psilocybin after escitalopram or placebo pretreatment in a randomized, double-blind, placebo-controlled, crossover study in healthy subjects