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CONCLUSION In conclusion, this case report demonstrates the promising role of L-carnitine and acetyl-L-carnitine supplementation in improving sperm quality, particularly in men with abnormal sperm morphology such as elongated sperms

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It is notable that high AR activity, rather than high AR expression per se, has been identified as a predictive biomarker of response to this treatment and transcriptional downregulation of AR has emerged as a mechanism of resistance to HD androgens in a subset of patients 33