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Importantly, de novo ser/gly synthesis pathway activation in lung cancer cells leads to increased GSH synthesis and folate-dependent NADPH production to regulate redox homeostasis, and enhanced purine synthesis to sustain proliferation [16,17,18]

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The supernatant was transferred, diluted with ddH 2 O, and SSA concentration adjusted to 0.5%

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EUROPE GLUTATHIONE MARKET SIZE, BY DIETARY SUPPLEMENTS, 2018-2032 (USD MILLION) TABLE 313