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Intriguingly, recent studies demonstrated that Al-tolerant maize roots secrets two benzoxazinoids such as DIMBOA (2,4-dihydroxy-7-methoxy-1,4-benzoxazin- 3-one) and MBOA (6-methoxy-benzoxazolin-2-one) to prevent Al entry into the root cells (Guimaraes et al., 2014

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In which, MMDX is nuclear-targeted analogue activated by the liver enzyme cytochrome P450 3A and metabolize into a cytotoxic metabolite and degrades slowly [103]

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