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Given continuous exposure to luminal antigens, the intestinal barrier plays a critical regulatory role by selectively permitting the passage of essential molecules while restricting the translocation of potentially harmful compounds [7]

Cell 181 , 914921.e10 (2020)

This effect is probably caused by the presence of sapogenins in fenugreek seeds, which stimulate bile secretion, enhance the metabolism of cholesterol to bile acids and cholesterol excretion

doi: 10.1016/0026-0495(77)90088-9 [DOI] [PubMed] [Google Scholar] 151.Luo Y, Kawashima A, Ishido Y, Yoshihara A, Oda K, Hiroi N, et al

The inverse relation between Ca2+ and PTH in the circulation obeys a sigmoidal curve (91)

Future research needs to focus on developing more targeted and efficient therapeutic strategies based on a deeper understanding of CAFs' biological characteristics, metabolic functions, and interactions with immune cells