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Microalgae accumulate different types of antioxidants, such as polysaccharides, carotenoids, sterols, vitamins (A, C, D, K, and E), flavonoids, amino acids, polyunsaturated fatty acids, minerals, sulfated polysaccharides, sulfolipids, peptides, coenzyme Q, phycocyanin, and scytonemin (a source of blue-green algae)

(9, 11) At the metabolic level, the signaling cascades that regulate bone metabolism offer some explanation for the obesity paradox

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Mitochondrial dysfunction compromises the energy supply of ATP to neurons, calcium homeostasis and leads to high levels of ROS that accelerate the mutation rate of mitochondrial DNA (mtDNA) and lipoperoxidation of neuronal membranes, causing decomposition of PUFAs and the formation of highly reactive end products: malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE) (the most toxic species related to cell damage and apoptosis) (Petrozzi et al., 2007

EBioMedicine 88:104432 Zhou N, Yuan X, Du Q et al (2023) FerrDb V2: update of the manually curated database of ferroptosis regulators and ferroptosis-disease associations