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Interestingly, ROS-mediated damage induced by antibiotics could be rescued by N-acetyl-l-cysteine (NAC) without affecting the antibiotics killing ability (97)

However, this increased dose also resulted in higher levels of Cyp3A4-derived Amb metabolites, whose clinical implications remain unclear

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Similarly, cleavage at four conjugated sites (Pro342-Thr343, Thr343-Pro344, Pro344-Arg345 and Arg345-Lys346) was detected in vivo for the active domain of jr PPO1 purified from leaves 34

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