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Acta Botanica Brasilica 25, 858864

Emerging evidence indicates that it is particularly associated with iron overload in the brain, especially in the hippocampus (Liu et al., 2020)

Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression

manufactured by Diagen, d.o.o., Ljubljana, Slovenia) (9-11, 13-24), morphine Merck 20 (Merck KGaA, Darmstadt, Germany), naloxone hydrochloride (Sigma-Aldrich, Germany), haloperidol (Sigma-Aldrich, Germany) were used