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Most dermatologists are not trained to provide what they often name as comfort or cosmetic treatment in terms of skin whitening treatment

These may include a gentle skincare routine, dermatologist-prescribed skincare products and avoiding sun exposure

Additionally, the paper reviews the role of ERS in RA, highlighting that immune system overactivation, excessive autoantibody production, and apoptosis resistance in RA-FLS are linked to ERS-mediated UPR responses

Proc Natl Acad Sci U S A 102:1154511550 Prisco S, Esposito E (1995) Differential effects of acute and chronic fluoxetine administration on the spontaneous activity of dopaminergic neurones in the ventral tegmental area

Similar to SARS- and MERS-CoV-induced symptoms, a subgroup of patients admitted to hospitals exhibit severe respiratory failure with dyspnea as observed in chest CT scans, bilateral lung infiltration, lymphopenia, muscle/joint pain, headache/dizziness, diarrhea, nausea, and coughing up of blood [3, 4, 6, 8, 10, 27,28,29]

Given that several hub proteins have been identified, further investigation of these proteins may provide deeper insights into the molecular mechanism of action of ATO from a systems perspective