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The transcriptional response of FOXO includes Ago-2 and Dcr-2 as well as other innate immune genes (163, 164)

This creates a vicious, self-perpetuating cycle of toxicity and inflammation that traps patients in a state of chronic illness, highlighting the desperate need for interventions that can physically bind and remove these substances

The expression levels of gshA and gshB were determined using real-time RT-PCR

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