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By 52% reduction in mortality rate of fruit flies and rats after epithalamin administration, and by 27% reduction in mortality rate of mice, compared to controls, was followed

For accurate determination of E GSH , the temperature is controlled in all measurements

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Immunofluorescence staining and quantitative RT-PCR confirmed that pyroptosis-related proteins cleaved-GSDMD, NLRP3, caspase-1, IL-1, and IL-18 were significantly enhanced in HG-stimulated SCs (106)

Considering that SELENOP is also involved in the defense against oxidative damage and had a q-value that was second (Welch t-test q = 0.08, log(FC) = 0.66) to GPx3 in this group comparisons using an untargeted approach, we sought to monitor peptides of both of these proteins by targeted LC-MS/MS (Supplementary Fig