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Progressive serum HBsAg reduction was closely paralleled with progressive serum HBeAg decline, implying that progressive serum HBsAg reduction reflects progressive HBV clearance in the livers, which was confirmed by a 3-4 log lower intrahepatic HBsAg, rc, and cccDNA levels from mice who achieved undetectable serum HBsAg compared to untreated controls

Obstet Gynecol (1992) 80(2):2835

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Injections are a routine part of medical care, used for vaccinations, medications, and other treatments